by undergoing a bone marrow transplant containing normal stem cells from a compatible donor.

by cloning stem cells in a medium containing normal genes for hemoglobin production.

by introducing normal genes into the genome of stem cells by means of viral vectors.

by producing transgenic stem cells in the laboratory, which are introduced into the hematopoietic tissue.

by the in vitro multiplication of stem cells modified by recombinant DNA techniques.

A French teenager, who underwent gene therapy to fight sickle cell anemia two years ago, now has enough red blood cells to contain the effects of the disease. In this case, the young man had hematopoietic tissue stem cells that underwent a treatment to prevent the formation of sickle blood cells. Today, approximately half of his red blood cells function normally; three months have already passed since he last needed medication or blood transfusion.

(http://oglobo.globo.com. Adapted.)

The treatment the teenager underwent is

Biologi

Gene therapy is the treatment the teenager underwent. It is a technique that aims to correct or prevent diseases by introducing normal genes into diseased cells. In this case, the patient's hematopoietic tissue stem cells were modified to contain a normal gene that prevents the formation of sickle blood cells. This genetic modification was performed by viral vectors, which are genetically modified and harmless viruses capable of transporting the normal gene to the genome of stem cells. After genetic modification, stem cells were reintroduced into the patient, where they differentiated into normal red blood cells, capable of fighting sickle cell anemia.

Pertanyaan tentang Genetika: Latihan

Mata Pelajaran Biologi

Biologi

Sumber UNIVAG

UNIVAG

Topik Genetika: Latihan

Genetika: Latihan

Tingkat Kesulitan Sedang

Sedang

(UNIVAG 2017) - Soal Sedang dari Biologi