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Question about Organic Functions: Ketone

Chemistry

Originais Teachy

Organic Functions: Ketone

Very Hard

(Originais Teachy 2023) - Question Very Hard of Chemistry

The synthesis of ketones is of great importance in the pharmaceutical and fragrance industry, where carbonyl compounds with carbonyl groups are often used as precursors. A classic example of ketone formation is the reaction of a primary amide with a strong base, followed by an acidic hydrolysis step. Consider the primary organic compound 'A', which has the structural formula C4H9CONH2, and that 'A' reacts with sodium hydroxide, followed by an acidic hydrolysis step, forming the organic compound 'B', a ketone. Discuss the detailed mechanism of the reactions involved, explaining the formation of the intermediate and the reason why 'B' is a ketone and not an aldehyde. Additionally, propose an experiment to characterize 'B' and differentiate it from an aldehyde with the same molecular formula as 'B.

Answer sheet:

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